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matricaria_chamomilla_l [2020/07/17 14:24] andreasmatricaria_chamomilla_l [2025/05/18 14:59] (aktuell) andreas
Zeile 14: Zeile 14:
 [Brunke E.-J., Hammerschmidt F.-J., Schmaus G., Flower scent of some traditional medicinal plants., in: Teranishi, R.;Buttery, R. G.;Sugisawa, H. Bioactive volatile compounds from plants. (Book) 1993, 282-296] [Brunke E.-J., Hammerschmidt F.-J., Schmaus G., Flower scent of some traditional medicinal plants., in: Teranishi, R.;Buttery, R. G.;Sugisawa, H. Bioactive volatile compounds from plants. (Book) 1993, 282-296]
  
-Extraction of the flowers (4kg) of M.chamomilla with hexane (yield: 80g extract) followed by column chromatography yielded mainly the [[https://www.thegoodscentscompany.com/data/rw1031831.html|balsamic sweet tonka-scented herniarin]] (1.76g), oleanolic acid,  stigmasterol, ß-sitosterol, and its glucoside. \\+Extraction of the flowers (4kg) of M.chamomilla with hexane (80g extract) followed by column chromatography yielded mainly the [[https://www.thegoodscentscompany.com/data/rw1031831.html|balsamic sweet tonka-scented herniarin]] (1.76g), oleanolic acid,  stigmasterol, ß-sitosterol, and its glucoside. \\
 [Ahmad, A., and L. N. Misra. "Isolation of herniarin and other constituents from Matricaria chamomilla flowers." International journal of pharmacognosy 35.2 (1997): 121-125] [[https://www.tandfonline.com/doi/pdf/10.1076/phbi.35.2.121.13280]] [Ahmad, A., and L. N. Misra. "Isolation of herniarin and other constituents from Matricaria chamomilla flowers." International journal of pharmacognosy 35.2 (1997): 121-125] [[https://www.tandfonline.com/doi/pdf/10.1076/phbi.35.2.121.13280]]
  
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 [Pro-apoptotic activity of a-bisabolol in preclinical models of primary human acute leukemia cells., Cavalieri, E., Rigo, A., Bonifacio, M., de Prati, A.C., Guardalben, E., Bergamini, C., Vinante, F., J Transl Med, Vol.9, 2011, 45] \\ [Pro-apoptotic activity of a-bisabolol in preclinical models of primary human acute leukemia cells., Cavalieri, E., Rigo, A., Bonifacio, M., de Prati, A.C., Guardalben, E., Bergamini, C., Vinante, F., J Transl Med, Vol.9, 2011, 45] \\
 [[http://www.biomedcentral.com/content/pdf/1479-5876-9-45.pdf]] [[http://www.biomedcentral.com/content/pdf/1479-5876-9-45.pdf]]
 +
 +Main volatile compounds of dried chamomile flowers collected with headspace solid-phase microextraction (HS-SPME) were (E)-β-farnesene (49%), artemisia ketone (10.1%), germacrene D (9.1%) and sabinene (7.7%). Interesting minor components not present in the essential oil (steam distillation-solvent extract, SDSE) were e.g. methyl 2-methylbutanoate (0.3%), ethyl 2-methyl butyrate (1.6%), propyl 2-methylbutanoate (0.5%), benzaldehyde (0.5%), and 1,8-cineole (2.2%). Main components of the essential oil were α-bisabolol oxide A (48.0%), chamazulene (20.4%), (E)-β-darnesene (6.7%) and (Z)-spiroether (6.7%). \\
 +[Rafieiolhossaini, Mohammad, et al. "Fast quality assessment of German chamomile (Matricaria chamomilla L.) by headspace solid-phase microextraction: influence of flower development stage." Natural Product Communications 7.1 (2012): 1934578X1200700133.]
  
 In chamomile tea, "...at most only 16% of the genuine essential oil can be extracted by infusion. High amounts of spiro ethers [cis- and trans-enyne-dicycloether] (ca.30% in the infusion vs. ca. 12% in the genuine oil) and coumarins (7%) [namely methylumbelliferone 5.5%] and reduced amounts of bisabolol oxides (ca. 32% in the infusion vs. ca. 60% in the genuine oil) can be regarded as markers of the volatile fraction of chamomile tea." \\ In chamomile tea, "...at most only 16% of the genuine essential oil can be extracted by infusion. High amounts of spiro ethers [cis- and trans-enyne-dicycloether] (ca.30% in the infusion vs. ca. 12% in the genuine oil) and coumarins (7%) [namely methylumbelliferone 5.5%] and reduced amounts of bisabolol oxides (ca. 32% in the infusion vs. ca. 60% in the genuine oil) can be regarded as markers of the volatile fraction of chamomile tea." \\
matricaria_chamomilla_l.1594995845.txt.gz · Zuletzt geändert: 2020/07/17 14:24 von andreas

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