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matricaria_chamomilla_l [2020/07/17 14:24] – andreasmatricaria_chamomilla_l [2026/07/21 16:04] (aktuell) – andreas
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 Extraction of the flowers (4kg) of M.chamomilla with hexane (80g extract) followed by column chromatography yielded mainly the [[https://www.thegoodscentscompany.com/data/rw1031831.html|balsamic sweet tonka-scented herniarin]] (1.76g), oleanolic acid,  stigmasterol, ß-sitosterol, and its glucoside. \\ Extraction of the flowers (4kg) of M.chamomilla with hexane (80g extract) followed by column chromatography yielded mainly the [[https://www.thegoodscentscompany.com/data/rw1031831.html|balsamic sweet tonka-scented herniarin]] (1.76g), oleanolic acid,  stigmasterol, ß-sitosterol, and its glucoside. \\
-[Ahmad, A., and L. N. Misra. "Isolation of herniarin and other constituents from Matricaria chamomilla flowers." International journal of pharmacognosy 35.2 (1997): 121-125] [[https://www.tandfonline.com/doi/pdf/10.1076/phbi.35.2.121.13280]]+[Ahmad, A., and L. N. Misra. "Isolation of herniarin and other constituents from Matricaria chamomilla flowers." International journal of pharmacognosy 35.2 (1997): 121-125] [[https://www.tandfonline.com/doi/pdf/10.1076/phbi.35.2.121.13280|PDF]]
  
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 Matricaria perforata (Geruchlose Kamille, 0.2%): (Z,Z)-matricaria ester (77.9%), (E)-β-farnesene (3.5%), matricaria ester isomer (3.5%), matricaria lactone (3.0%). \\ Matricaria perforata (Geruchlose Kamille, 0.2%): (Z,Z)-matricaria ester (77.9%), (E)-β-farnesene (3.5%), matricaria ester isomer (3.5%), matricaria lactone (3.0%). \\
 [Content and composition of essential oils in some Asteraceae species., Raal, A., Kaur, H., Orav, A., Arak, E., Kailas, T., Muurisepp, M., Proceedings of the Estonian Academy of Sciences, Vol.60(1), 2011, 55-63] \\ [Content and composition of essential oils in some Asteraceae species., Raal, A., Kaur, H., Orav, A., Arak, E., Kailas, T., Muurisepp, M., Proceedings of the Estonian Academy of Sciences, Vol.60(1), 2011, 55-63] \\
-[[http://kirj.ee/public/proceedings_pdf/2011/issue_1/proc-2011-1-55-63.pdf]]+[[http://kirj.ee/public/proceedings_pdf/2011/issue_1/proc-2011-1-55-63.pdf|PDF]]
  
 "α-Bisabolol enters cells via lipid rafts, binds to the pro-apoptotic Bcl-2 family protein BID... α-bisabolol is a pro-apoptotic agent for primary human acute leukemia cells... the pro-apoptotic action of α-bisabolol is not dependent on BID cleavage. However, caspase cleavage is not an absolute requirement for activating BID pro-apoptotic function. Full-length BID is also capable of translocation to the mitochondria, where it has been shown to potentiate cell death following certain apoptotic signals. But we were unable to demonstrate full-length BID in the mitochondria by separating cytosolic and mitochondrial fraction following α-bisabolol treatment" \\ "α-Bisabolol enters cells via lipid rafts, binds to the pro-apoptotic Bcl-2 family protein BID... α-bisabolol is a pro-apoptotic agent for primary human acute leukemia cells... the pro-apoptotic action of α-bisabolol is not dependent on BID cleavage. However, caspase cleavage is not an absolute requirement for activating BID pro-apoptotic function. Full-length BID is also capable of translocation to the mitochondria, where it has been shown to potentiate cell death following certain apoptotic signals. But we were unable to demonstrate full-length BID in the mitochondria by separating cytosolic and mitochondrial fraction following α-bisabolol treatment" \\
-[Pro-apoptotic activity of a-bisabolol in preclinical models of primary human acute leukemia cells., Cavalieri, E., Rigo, A., Bonifacio, M., de Prati, A.C., Guardalben, E., Bergamini, C., Vinante, F., J Transl Med, Vol.9, 2011, 45] \\ +[Pro-apoptotic activity of a-bisabolol in preclinical models of primary human acute leukemia cells., Cavalieri, E., Rigo, A., Bonifacio, M., de Prati, A.C., Guardalben, E., Bergamini, C., Vinante, F., J Transl Med, Vol.9, 2011, 45] [[http://www.biomedcentral.com/content/pdf/1479-5876-9-45.pdf|PDF]] 
-[[http://www.biomedcentral.com/content/pdf/1479-5876-9-45.pdf]]+ 
 +Main volatile compounds of dried chamomile flowers collected with headspace solid-phase microextraction (HS-SPME) were (E)-β-farnesene (49%), artemisia ketone (10.1%), germacrene D (9.1%) and sabinene (7.7%). Interesting minor components not present in the essential oil (steam distillation-solvent extract, SDSE) were e.g. methyl 2-methylbutanoate (0.3%), ethyl 2-methyl butyrate (1.6%), propyl 2-methylbutanoate (0.5%), benzaldehyde (0.5%), and 1,8-cineole (2.2%). Main components of the essential oil were α-bisabolol oxide A (48.0%), chamazulene (20.4%), (E)-β-darnesene (6.7%) and (Z)-spiroether (6.7%). \\ 
 +[Rafieiolhossaini, Mohammad, et al. "Fast quality assessment of German chamomile (Matricaria chamomilla L.) by headspace solid-phase microextraction: influence of flower development stage." Natural Product Communications 7.1 (2012): 1934578X1200700133.]
  
 In chamomile tea, "...at most only 16% of the genuine essential oil can be extracted by infusion. High amounts of spiro ethers [cis- and trans-enyne-dicycloether] (ca.30% in the infusion vs. ca. 12% in the genuine oil) and coumarins (7%) [namely methylumbelliferone 5.5%] and reduced amounts of bisabolol oxides (ca. 32% in the infusion vs. ca. 60% in the genuine oil) can be regarded as markers of the volatile fraction of chamomile tea." \\ In chamomile tea, "...at most only 16% of the genuine essential oil can be extracted by infusion. High amounts of spiro ethers [cis- and trans-enyne-dicycloether] (ca.30% in the infusion vs. ca. 12% in the genuine oil) and coumarins (7%) [namely methylumbelliferone 5.5%] and reduced amounts of bisabolol oxides (ca. 32% in the infusion vs. ca. 60% in the genuine oil) can be regarded as markers of the volatile fraction of chamomile tea." \\
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 {{kamille.jpg?600}} \\ {{kamille.jpg?600}} \\
-Fuchs, L., New Kreüterbuch, t. 14 (1543) \\ +Fuchs, L., New Kreüterbuch, t. 14 (1543) [[http://plantgenera.org/species.php?id_species=647584|plantgenera.org]]
-[[http://plantgenera.org/species.php?id_species=647584]]+
  
  
 {{http://www.botanische-spaziergaenge.at/Bilder/Konica_4/PICT1645.JPG}} \\ {{http://www.botanische-spaziergaenge.at/Bilder/Konica_4/PICT1645.JPG}} \\
-Matricaria chamomilla \\ © Rolf Marschner (2007),   +Matricaria chamomilla © Rolf Marschner (2007) [[http://botanische-spaziergaenge.at/viewtopic.php?f=131&t=2683| botanische-spaziergaenge.at]]
-[[http://botanische-spaziergaenge.at/viewtopic.php?f=131&t=2683| www.botanische-spaziergaenge.at]]+
matricaria_chamomilla_l.1594995865.txt.gz · Zuletzt geändert: 2020/07/17 14:24 von andreas
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